Peptide Hormones Thymosin Alpha 1 Acetate/Serilesine/Eptifibatide/Desmopressin Acetate For Muscle Mass 16789-98-3

Basic Info

Desmopressin Acetate

Other Name: Thymosin Alpha 1 Acetate 

CAS 16789-98-3

Alias: DDAVP, 1-Deamino-8-D-arginine-vasopressin diacetate, 1-(3-Mercaptopropionic acid)-8-D-arginine-vasopressin diacetate

CAS No.: 16789-98-3

Molecular Formula: C46H64N14O12S2

Molecular Weight: 1189.32

Purity (HPLC): 98.0%min.

Appearance: White powder

Single Impurity (HPLC): 0.5%max

Amino Acid Composition: ± 10% of theoretical

Peptide Content (N%): ≥ 80.0%

Water Content (Karl Fischer): ≤ 8.0%

Acetate Content (HPIC): ≤ 12.0%

MS (ESI): Consistent

Mass Balance: 95.0~105.0%

Grade: Pharmaceutical Grade

Storage: Closed, below 2 ~ 8º C preservation

Usage: Desmopressin Acetate is used for nocturnal enuresis, coagulation zdisorders and diabetes insipidus.

Desmopressin (trade names: DDAVP, DesmoMelt, Minirin, Minirin Melt, Octim, Stimate) is a synthetic replacement for vasopressin, the hormone that reduces urine production. It may be taken nasally, intravenously, or as an oral or sublingual tablet. Physicians prescribe desmopressin most frequently for treatment of diabetes insipidus, bedwetting, or nocturia.

Introduction of "Peptide"

Peptide is a connect with peptides and amino acids, but each of these peptides can consist of a variety of amino acids. Two kinds of amino acid composition of call two peptides, three kinds of amino acids is composed of three peptides, and so on. Now hear the three peptides, five peptides, even nine peptide, belong to the peptide chain. Each of the peptide chain has a different effect. Usually less than 10 amino acid peptide called oligopeptide, called polypeptide amino acids for more, more than 50 called protein. Because of containing amino acid of different varieties and two peptides, three peptides have different varieties, thus arises now has all kinds of action, all kinds of names "peptide".

Description

Desmopressin ( trade names : DDAVP , DesmoMelt , Minirin , Minirin Melt , Octim , Stimate ) is a synthetic replacement for vasopressin , the hormone that reduces urine production . It may be taken nasally , intravenously , or as an oral or sublingual tablet . Physicians prescribe desmopressin most frequently for treatment of diabetes insipidus , bedwetting , or nocturia .

Application

Doctors prescribe desmopressin frequently for treatment of nocturnal enuresis ( bedwetting ) . It is usually prescribed in the form of oral desmopressin acetate , DDAVP . Patients taking DDAVP are 4.5 times more likely to sleep without disruption compared with placebo .

Desmopressin can be used to promote the release of von Willebrand factor ( with subsequent increase in factor VIII survival secondary to vWF complexing ) in patients with coagulation disorders such as von Willebrand disease, mild hemophilia A ( factor VIII deficiency ) , and thrombocytopenia . It can be used with uremic induced platelet dysfunction . It is not effective in the treatment of hemophilia B ( factor IX deficiency ) , severe hemophilia A , or von Willebrand 2B .

Desmopressin is used in the treatment of central diabetes insipidus ( DI ) , to replace endogenous ADH that is missing in the central nervous system type of this disorder ( decreased production of ADH from the posterior pituitary ) . It is also used in the diagnostic workup for diabetes insipidus , in order to distinguish central from nephrogenic DI .

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